Non Systemic Insecticide Pesticide Emamectin Benzoate 5% WDG CAS 155569-91-8

Non Systemic Insecticide Pesticide Emamectin Benzoate 5% WDG CAS 155569-91-8

PHYSICAL CHEMISTRY

emamectin benzoate

Composition A mixture of emamectin B1a (³90%) and emamectin B1b (£10%), as their benzoate salts. Mol. wt. 1008.3 (B1a); 994.2 (B1b) M.f. C56H81NO15 (B1a); C55H79NO15 (B1b) Form White to off-white powder. M.p. 141-146 °C V.p. 4 ´ 10-3 mPa (21 °C) KOW logP = 5.0 (pH 7) S.g./density 1.20 (23 °C) Solubility In water 0.024 g/l (pH 7, 25°C).

emamectin

Mol. wt. 886.1 (B1a); 872.1 (B1b) M.f. C49H75NO13 (B1a); C48H73NO13 (B1b)

APPLICATIONS

emamectin benzoate

Biochemistry Acts by stimulating the release of g-aminobutyric acid, an inhibitory neurotransmitter, thus causing paralysis. Mode of action Non-systemic insecticide which penetrates leaf tissues by translaminar movement. Paralyses the lepidoptera, which stop feeding within hours of ingestion, and die 2-4 dat. Uses For control of Lepidoptera on vegetables, brassicas and cotton, at up to 16 g/ha, and in pine trees, at 5-25 g/ha.

MAMMALIAN TOXICOLOGY

emamectin benzoate

Oral Acute oral LD50 for rats 76-89 mg/kg. Skin and eye Acute dermal LD50 for rabbits >2000 mg/kg. It is not irritant to skin, and has no sensitising potential. Inhalation LC50 (4 h) for rats 2.12-4.44 mg/m3. NOEL (1 y) for dogs 0.25 mg/kg b.w. ADI 0.0025 mg/kg. Other Not tumorigenic. Toxicity class WHO (a.i.) II (company classification)

ECOTOXICOLOGY

emamectin benzoate

Birds Acute oral LD50 for mallard ducks 46, bobwhite quail 264 mg/kg. Dietary LC50 (8 d) for mallard ducks 570, bobwhite quail 1318 ppm. Fish LC50 (96 h) for rainbow trout 174, sheepshead minnow 1430 mg/l. Daphnia LC50 0.99 mg/l. Bees Toxic to bees. Worms LC50 >1000 mg/kg dry soil. Other beneficial spp. Safe to a wide range of beneficial insects, due rapid breakdown of the a.i., limiting contact activity to <48 h.

ENVIRONMENTAL FATE

Animals Emamectin benzoate is partially metabolised but rapidly cleared (DT50 following oral dosing 34-51 h), indicating that it has no potential for bioaccumulation. Plants Metabolism has been investigated in lettuce, cabbage and sweet corn. It is non-systemic, and rapidly degrades in sunlight to various complex residues in which undegraded parent is the only significant residue. The residues were very low. Soil/Environment Rapidly degraded.