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Propamocarb hydrochloride 72.2% SL CAS NO. 25606-41-1 Systemic fungicide with protective action

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Propamocarb hydrochloride 72.2% SL CAS NO. 25606-41-1 Systemic fungicide with protective action

Brand Name : MOLOTUS
Model Number : propamocarb hydrochloride 72.2% SL
Certification : ISO
Place of Origin : CHINA
MOQ : Negotiable
Price : Negotiable
Payment Terms : L/C, T/T, D/P, D/A
Delivery Time : 20-25 days
Packaging Details : 200L, 20L, 5L, 1L, 500ML, 250ML, 100ML
Active Ingredient : propamocarb hydrochloride
CAS NO. : 25606-41-1
Chemicals Name : propyl [3-(dimethylamino)propyl]carbamate hydrochloride
How to Act : Absorbed by the roots and leaves, and transported acropetally.
M.f. : C9H21ClN2O2
Classification : Systemic fungicide
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propamocarb hydrochloride


propamocarb hydrochloride

IUPAC name propyl 3-(dimethylamino)propylcarbamate hydrochloride

Chemical Abstracts name propyl [3-(dimethylamino)propyl]carbamate hydrochloride

CAS RN [25606-41-1] EEC no. 247-125-9


Common name propamocarb (BSI, E-ISO, ANSI); propamocarbe ((m) F-ISO)

IUPAC name propyl 3-(dimethylamino)propylcarbamate

Chemical Abstracts name propyl [3-(dimethylamino)propyl]carbamate

CAS RN [24579-73-5]


propamocarb hydrochloride

Composition The aqueous concentrate contains 780 g/l propamocarb hydrochloride. Mol. wt. 224.7 M.f. C9H21ClN2O2 Form Colourless, faintly aromatic, hygroscopic crystals. M.p. 64.2 °C V.p. 3.85 ´ 10-2 mPa (20 °C) KOW logP = -1.21 (pH 7) Henry <1.7 ´ 10-8 Pa m3 mol-1 (20 °C, calc.) S.g./density 1.085 g/ml (20 °C, aqueous concentrate) Solubility In water >500 g/l (20 °C). In methanol 656, dichloromethane >626, acetone 560, ethyl acetate 4.34, toluene 0.14, hexane <0.01 (all in g/l, 20 °C). Stability Stable to hydrolysis, to temperatures up to 400 ºC, and to photolysis. pKa 9.3 (20 °C) Other properties Surface tension 40.9 mN m-1 (40 °C).


Mol. wt. 188.3 M.f. C9H20N2O2 V.p. 730 mPa (25 °C) KOW logP = 0.84 (20 °C) Henry 1.5 ´ 10-4 Pa m3 mol-1 (25 °C) Solubility In water >900 g/l (pH 7.0, 20 °C). In hexane >883, methanol >933, dichloromethane >937, toluene >852, acetone >921, ethyl acetate >856 (all in g/l, 20 °C). pKa 9.5, strong base (K. Chamberlain et al., Pestic. Sci., 47,265 (1996))


Biochemistry Reduces mycelial growth and development of sporangia and (zoo)spores; influences the biochemical synthesis of membranes. Mode of action Systemic fungicide with protective action. Absorbed by the roots and leaves, and transported acropetally.


Product analysis by lc with u.v. detection (CIPAC Handbook, 1992, E, 184-6). Residues determined by glc with FID (I. A. Gentile & E. Passera, J. Chromatogr., 1982, 236,254). Methods for the determination of residues are available upon request from Bayer CropScience.


Reviews FAO/WHO 47, 49 (see part 2 of the Bibliography).

propamocarb hydrochloride

Oral Acute oral LD50 for rats 2000-2900, mice 2650-2800, dogs c. 1450 mg/kg. Skin and eye Acute percutaneous LD50 for rats and mice >3000 mg/kg. Not a skin or eye irritant (rabbits). Not a skin sensitiser. Inhalation LC50 (4 h) for rats >5.54 mg/l air. NOEL (2 y) for rats 26-32 mg/kg b.w. ADI (JMPR) 0.1 mg/kg b.w. (for base) [1986].; 0.4 mg/kg b.w. (company proposed) Other Negative in Ames and micronucleus tests. Not teratogenic in rats and rabbits, no reproductive, developmental or carcinogenic effects. EC classification (Xi; R43)


Inhalation LC50 (4 h) for rats >3.96 mg/l air. Toxicity class WHO (a.i.) U; EPA (formulation) IV


propamocarb hydrochloride

Birds Acute oral LD50 for bobwhite quail and mallard duck >1842 mg/kg. Dietary LC50 for bobwhite quail and mallard duck >4789 mg/kg. Fish LC50 (96 h) for bluegill sunfish >92, for rainbow trout >99 mg/l. Daphnia LC50 (48 h) 106 mg/l. Algae ErC50 (72 h) for Selenastrum capricornutum >85 mg/l; EbC50 >120 mg/l. Other aquatic spp. EC50 (96 h) for Eastern oyster (Crassostrea virginica) 43.9 mg/l; LC50 (96 h) for mysid shrimp (Mysidopsis bahia) 105 mg/l. Bees LD50 (oral) >84 µg/bee; (contact) >100 µg/bee. Worms LC50 (14 d) >660 mg/kg soil.


Animals Rapidly absorbed and almost totally excreted (>90% in 24 h), mainly via urine. Mineralisation occurs via oxidation and hydrolytic decomposition. Plants Mainly unchanged in plants. Soil/Environment Rapidly degraded in soil by microbial processes, following a brief lag phase, DT50 <30 d, DT90 <70 d. Propamocarb hydrochloride is retained in the upper soil layer (4-20 cm) and little is found in leachate. Stable in aqueous medium, but rapidly degraded by aquatic micro-organisms (up to 97% in 35 d). It is adsorbed onto sediment, but with limited desorption.

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